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Energy-aware fuzzy job-shop scheduling for engine remanufacturing at the multi-machine level

Jiali ZHAO, Shitong PENG, Tao LI, Shengping LV, Mengyun LI, Hongchao ZHANG

Frontiers of Mechanical Engineering 2019, Volume 14, Issue 4,   Pages 474-488 doi: 10.1007/s11465-019-0560-z

Abstract: An improved adaptive genetic algorithm was developed by using the hormone modulation mechanism to deal

Keywords： remanufacturing scheduling     adaptive genetic algorithm     energy efficiency     sustainable remanufacturing     hormonemodulation mechanism    

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Atypical pituitary hormone–target tissue axis

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 1-17 doi: 10.1007/s11684-022-0973-7

Abstract: However, a number of studies have shown that multiple types of pituitary hormone receptors are widelyEach pituitary gland-derived hormone exhibits a wide range of nonconventional biological effects in thesehormone, luteinizing hormone, adrenocorticotrophic hormone, and prolactin when they act on non-classicalorgans were summarized, defined by the novel concept of an “atypical pituitary hormone–target tissueThe continued exploration of the physiology of the “atypical pituitary hormone–target tissue axis” could

Keywords： thyroid-stimulating hormone     follicle-stimulating hormone     luteinizing hormone     adrenocorticotrophichormone     prolactin    

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Clinical evaluation of recombinant human growth hormone injection in children with growth hormone deficiency

Ling HOU, Xiaoping LUO, Minlian DU, Huamei MA, Chunxiu GONG, Yuchuan LI, Shuixian SHEN, Zhuhui ZHAO, Li LIANG, Guanping DONG, Chaoying YAN, Hongwei DU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 171-176 doi: 10.1007/s11684-009-0027-4

Abstract: Recombinant human growth hormone (rhGH) has been widely used in the clinical treatment of growth hormonecurrent study was to evaluate the efficacy and safety of rhGH injection for the treatment of growth hormoneWe conclude that rhGH injection is a safe and effective drug for treatment of growth hormone deficiency

Keywords： recombinant human growth hormone     injection     growth hormone deficiency    

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How to judge the association of postmenopausal hormone therapy and the risk of breast cancer

Ling XU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 290-293 doi: 10.1007/s11684-010-0093-7

Abstract: The relevance of postmenopausal hormone therapy (HT) for breast cancer risk has been long debated, although

Keywords： breast cancer     postmenopausal hormone therapy     unopposed estrogen therapy     combined estrogen-progestin therapy    

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Sensitivity of supplementation of thyroid hormone on treatment of idiopathic short-stature children duringtherapy with recombinant human growth hormone

Wei Wang, Shuqin Jiang, Zhirui Cui, Xiangyang Luo, Lingli Shi, Heli Zheng

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 580-585 doi: 10.1007/s11684-017-0585-9

Abstract:

This study aimed to evaluate the effects of thyroid hormone supplementation on growth rate of childrenwith idiopathic short stature (ISS) and low-normal serum free thyroxine FT4 who were receiving growth hormoneDuring the first year, the lower FT4 group featured lower FT3, FT4, thyroid stimulating hormone (TSH)In children with ISS, the negative effect of thyroid hormone deficiency on growth rate should be consideredwhen FT4 level lies in the low-normal range prior to recombinant human growth hormone treatment.

Keywords： therapeutic     idiopathic short-stature children     free T4     the first year     recombinant human growth hormone    

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Pituitary-ovarian hormone and follicular development of various combined oral contraceptives regimens

Huang Pei,Huang Xunbin

Strategic Study of CAE 2015, Volume 17, Issue 6,   Pages 16-20

Abstract: of estrogen and progestin, secondarily leading to suppression of endogenous gonadotropin and gonadal hormoneDuring the hormone-free interval (HFI), COCs users experience activation of their pituitary–ovarian

Keywords： COCs     HFI     hormone     follicle    

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RECENT ADVANCES IN THE REGULATION OF CLIMACTERIC FRUIT RIPENING: HORMONE, TRANSCRIPTION FACTOR AND EPIGENETIC

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2,

Abstract:

Fruit ripening is a complex developmental process made up of genetically programmed physiological and biochemical activities. It culminates in desirable changes in the structural and textural properties and is governed by a complex regulatory network. Much is known about ethylene, one of the most important metabolites promoting the ripening of climacteric fruits. However, the dynamic interplay between phytohormones also plays an important part. Additional regulatory factors such as transcription factors (TFs) and epigenetic modifications also play vital role in the regulation of climacteric fruit ripening. Here, we review and evaluate the complex regulatory network comprising interactions between hormones and the action of TFs and epigenetic modifications during climacteric fruit ripening.

 

Keywords： climacteric fruit ripening / phytohormones / TFs / epigenetic modifications    

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High efficiency spreading spectrum modulation based on double orthogonal complex sequences

Shi Xiaohong

Strategic Study of CAE 2012, Volume 14, Issue 3,   Pages 108-112

Abstract:

This paper presents a kind of high efficiency spreading spectrum modulation

Keywords： modulation and demodulation     high efficiency spreading spectrum modulation     forward phase correction    

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RECENT ADVANCES IN THE REGULATION OF CLIMACTERIC FRUIT RIPENING: HORMONE, TRANSCRIPTION FACTOR AND EPIGENETIC

Yinglin JI, Mingyang XU, Aide WANG

Frontiers of Agricultural Science and Engineering   Pages 314-334 doi: 10.15302/J-FASE-2021386

Abstract: Fruit ripening is a complex developmental process made up of genetically programmed physiological and biochemical activities. It culminates in desirable changes in the structural and textural properties and is governed by a complex regulatory network. Much is known about ethylene, one of the most important metabolites promoting the ripening of climacteric fruits. However, the dynamic interplay between phytohormones also plays an important part. Additional regulatory factors such as transcription factors (TFs) and epigenetic modifications also play vital role in the regulation of climacteric fruit ripening. Here, we review and evaluate the complex regulatory network comprising interactions between hormones and the action of TFs and epigenetic modifications during climacteric fruit ripening.

Keywords： climacteric fruit ripening     phytohormones     TFs     epigenetic modifications    

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A driving pulse edge modulation technique and its complex programming logic devices implementation

Xiao CHEN,Dong-chang QU,Yong GUO,Guo-zhu CHEN

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 12,   Pages 1088-1098 doi: 10.1631/FITEE.1500111

Abstract: This paper describes a new technique of driving pulse edge modulation for insulated gate bipolar transistors

Keywords： Driving pulse edge modulation     Switching voltage spike     Complex programmable logic device (CPLD)     Active    

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Cannabidiol prevents depressive-like behaviors through the modulation of neural stem cell differentiation

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 227-239 doi: 10.1007/s11684-021-0896-8

Abstract: Therefore, investigating the mechanism of neural differentiation and AHN is of great importance for developingprevented rNSCs overactivation and differentiation into astrocyte, which was partly mediated by the modulationThese results revealed a previously unknown neural mechanism for neural differentiation and AHN in depression

Keywords： cannabidiol     depression     radial neural stem cells     neurogenesis    

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The study of ovary development and steroid hormone changes in Alosa sapidissima

Hong Lei,Li Zhaoxin,Chen Chao,Guo Zhenglong,Wang Weifang,Lei Jilin

Strategic Study of CAE 2014, Volume 16, Issue 9,   Pages 86-92

Abstract:

In this study, the morphological changes of ovary development and variation of correlated plasma sex steroids levels were detected in Alosa sapidissima. The result shown that Alosa sapidissima belongs to the non-synchronized multiple batch spawner; based on size, shape and external color, the development of ovary was divided into six stages; according to changes of inner structures, yolk accumulating and development of follicle cells, the oogenesis could be divided into six phases. There were no significant differences about hepatosomatic index (HSI) and condition factor (CF) during the ovarian maturation cycle, but gonadosomatic index (GSI) and 17β- estradiol (E2) were found to increase during the peak phase of vitellogenic growth corresponding to the ovary development.

Keywords： Alosa sapidissima     ovary development     oogenesis     histology     morphology     steroid hormone    

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Overcoming resistance to endocrine therapy in hormone receptor-positive human epidermal growth factor

Wenjie Zhu, Binghe Xu

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 208-220 doi: 10.1007/s11684-020-0795-4

Abstract: New targeted therapies have been developed to overcome resistance to endocrine therapy (ET) and improve the outcome of HR /HER2 advanced breast cancer (ABC). We conducted a meta-analysis and systemic review on randomized controlled trials evaluating various targeted therapies in combination with ET in HR /HER2 ABC. PUBMED and EMBASE databases were searched for eligible trials. Hazard ratios (HRs) for progression-free survival (PFS), odds ratios (ORs) for objective response rate (ORR), clinical benefit rate (CBR), and toxicity were meta-analyzed. Twenty-six studies with data on 10 347 patients were included and pooled. The addition of cyclin-dependent kinase 4/6 inhibitors to ET significantly improved median PFS (pooled HR= 0.547, <0.001), overall survival (pooled HR= 0.755, <0.001), and tumor response rates (ORR, pooled OR= 1.478, <0.001; CBR, pooled OR= 1.201, <0.001) with manageable toxicities (pooled OR= 3.280, <0.001). The mammalian targets of rapamycin inhibitors and exemestane were not clinically beneficial for this pooled population including ET-naïve and ET-resistant patients. Moderate improvement in PFS (pooled HR= 0.686, <0.001) yet pronounced toxicities (pooled OR= 2.154, <0.001) were noted in the combination of phosphatidylinositol-4,5-bisphosphate 3-kinase inhibitors with fulvestrant. Future studies are warranted to optimize the population and the dosing sequence of these available options.

Keywords： endocrine-resistant     HR+/HER2- advanced breast cancer     randomized clinical trials     meta-analysis     targeted therapy    

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Modulation of Gut Microbiota in Pathological States

Yulan Wang, Baohong Wang, Junfang Wu, Xiangyang Jiang, Huiru Tang, Ole H. Nielsen

Engineering 2017, Volume 3, Issue 1,   Pages 83-89 doi: 10.1016/J.ENG.2017.01.013

Abstract:

The human microbiota is an aggregate of microorganisms residing in the human body, mostly in the gastrointestinal tract (GIT). Our gut microbiota evolves with us and plays a pivotal role in human health and disease. In recent years, the microbiota has gained increasing attention due to its impact on host metabolism, physiology, and immune system development, but also because the perturbation of the microbiota may result in a number of diseases. The gut microbiota may be linked to malignancies such as gastric cancer and colorectal cancer. It may also be linked to disorders such as nonalcoholic fatty liver disease (NAFLD); obesity and diabetes, which are characterized as “lifestyle diseases” of the industrialized world; coronary heart disease; and neurological disorders. Although the revolution in molecular technologies has provided us with the necessary tools to study the gut microbiota more accurately, we need to elucidate the relationships between the gut microbiota and several human pathologies more precisely, as understanding the impact that the microbiota plays in various diseases is fundamental for the development of novel therapeutic strategies. Therefore, the aim of this review is to provide the reader with an updated overview of the importance of the gut microbiota for human health and the potential to manipulate gut microbial composition for purposes such as the treatment of antibiotic-resistant Clostridium difficile (C. difficile) infections. The concept of altering the gut community by microbial intervention in an effort to improve health is currently in its infancy. However, the therapeutic implications appear to be very great. Thus, the removal of harmful organisms and the enrichment of beneficial microbes may protect our health, and such efforts will pave the way for the development of more rational treatment options in the future.

Keywords： Gut microbes     Diseases     Microbial modulation    

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Gut Microbiota Modulation: A Viable Strategy to Address Medical Needs in Hepatocellular Carcinoma and Review

Ze Xiang, Jian Wu, Jiarui Li, Shusen Zheng, Xuyong Wei, Xiao Xu

Engineering 2023, Volume 29, Issue 10,   Pages 59-72 doi: 10.1016/j.eng.2022.12.012

Abstract: be emphasized, which can provide new insights into the management of HCC and LT via gut microbiota modulation

Keywords： Gut microbiota     Hepatocellular carcinoma (HCC)     Liver transplantation (LT)     Clinical value     Mediating mechanism    

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Title Author Date Type Operation

Energy-aware fuzzy job-shop scheduling for engine remanufacturing at the multi-machine level

Jiali ZHAO, Shitong PENG, Tao LI, Shengping LV, Mengyun LI, Hongchao ZHANG

Journal Article

Atypical pituitary hormone–target tissue axis

Journal Article

Clinical evaluation of recombinant human growth hormone injection in children with growth hormone deficiency

Ling HOU, Xiaoping LUO, Minlian DU, Huamei MA, Chunxiu GONG, Yuchuan LI, Shuixian SHEN, Zhuhui ZHAO, Li LIANG, Guanping DONG, Chaoying YAN, Hongwei DU

Journal Article

How to judge the association of postmenopausal hormone therapy and the risk of breast cancer

Ling XU

Journal Article

Sensitivity of supplementation of thyroid hormone on treatment of idiopathic short-stature children duringtherapy with recombinant human growth hormone

Wei Wang, Shuqin Jiang, Zhirui Cui, Xiangyang Luo, Lingli Shi, Heli Zheng

Journal Article

Pituitary-ovarian hormone and follicular development of various combined oral contraceptives regimens

Huang Pei,Huang Xunbin

Journal Article

RECENT ADVANCES IN THE REGULATION OF CLIMACTERIC FRUIT RIPENING: HORMONE, TRANSCRIPTION FACTOR AND EPIGENETIC

Journal Article

High efficiency spreading spectrum modulation based on double orthogonal complex sequences

Shi Xiaohong

Journal Article

RECENT ADVANCES IN THE REGULATION OF CLIMACTERIC FRUIT RIPENING: HORMONE, TRANSCRIPTION FACTOR AND EPIGENETIC

Yinglin JI, Mingyang XU, Aide WANG

Journal Article

A driving pulse edge modulation technique and its complex programming logic devices implementation

Xiao CHEN,Dong-chang QU,Yong GUO,Guo-zhu CHEN

Journal Article

Cannabidiol prevents depressive-like behaviors through the modulation of neural stem cell differentiation

Journal Article

The study of ovary development and steroid hormone changes in Alosa sapidissima

Hong Lei,Li Zhaoxin,Chen Chao,Guo Zhenglong,Wang Weifang,Lei Jilin

Journal Article

Overcoming resistance to endocrine therapy in hormone receptor-positive human epidermal growth factor

Wenjie Zhu, Binghe Xu

Journal Article

Modulation of Gut Microbiota in Pathological States

Yulan Wang, Baohong Wang, Junfang Wu, Xiangyang Jiang, Huiru Tang, Ole H. Nielsen

Journal Article

Gut Microbiota Modulation: A Viable Strategy to Address Medical Needs in Hepatocellular Carcinoma and

Ze Xiang, Jian Wu, Jiarui Li, Shusen Zheng, Xuyong Wei, Xiao Xu

Journal Article